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.bio-intro{max-width:800px;margin:0 0 24px;color:#56677e}
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@media(max-width:1050px){.bio-workspace{grid-template-columns:minmax(0,1fr)}.bio-map{border-right:0;border-bottom:1px solid #d7e1f0;display:grid;grid-template-columns:1fr 1fr;gap:0 25px}.bio-map-heading{grid-column:1/-1}.bio-map-caption{border:0;margin:0;padding:0}.bio-circuit,.bio-follicle{width:100%}}
@media(max-width:650px){.bio-map{display:block;padding:22px 18px}.bio-selection{padding:22px 18px}.bio-map-heading h2{font-size:1.9rem}.bio-map-caption{border-top:1px solid #cfdaea;margin-top:20px;padding-top:18px}.bio-filters{gap:6px}.bio-filters button{padding:9px 11px}.bio-record>summary>.bio-status{display:table;margin:8px 0 0}.bio-trial-context>div{grid-template-columns:85px minmax(0,1fr)}.bio-trial-plot{padding:15px 12px}.bio-effect-number{font-size:1.8rem}.bio-map-heading{margin-bottom:20px}.bio-circuit{max-width:340px}.bio-follicle{max-width:330px}}
@media(prefers-reduced-motion:reduce){.bio-explorer *{scroll-behavior:auto}}

.bio-treatment-control{max-width:620px;margin-bottom:4px}.bio-bar-zero{position:absolute;top:0;bottom:0;border-left:1px solid #59718f;z-index:1}.bio-selection>.bio-interpretation{font-size:.9375rem;color:#435d80}

/* Sleep pathways and controls are scoped so the hair explorer remains unchanged. */
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.bio-sleep .bio-mechanism-control>label{display:block;font-size:.875rem;font-weight:600;margin-bottom:9px}
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.bio-sleep .bio-treatment-control{max-width:none}.bio-sleep .bio-treatment-filters select:focus-visible{outline:2px solid var(--bio-blue);outline-offset:3px}
.bio-sleep .bio-workspace{animation:bioSleepReveal 180ms ease-out}
@keyframes bioSleepReveal{from{opacity:.55}to{opacity:1}}
.bio-pathway .bio-circuit-origin{padding:20px 18px}.bio-pathway .bio-circuit-origin>strong{font-size:1.8rem;line-height:1.2}
.bio-pathway .bio-receptor-row{flex-wrap:wrap;gap:8px}.bio-pathway .bio-receptor{min-width:76px;padding:9px 15px;font-size:.9375rem;line-height:1.4}
.bio-pathway[data-bio-diagram-mode=behavioral] .bio-receptor{border-radius:8px;font-size:.8125rem;min-width:0;flex:1 1 100px;padding:10px 8px}
.bio-pathway .bio-signal-link{margin:5px 0;gap:9px;text-align:center}.bio-pathway .bio-signal-link b{max-width:245px;line-height:1.45}
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.bio-pathway-note{font-size:.75rem;color:#72849d;text-align:center;margin:10px 0 0;line-height:1.5}
.bio-sleep .bio-guideline-context{padding:12px 14px;background:#f4f7fc;border-left:3px solid #a4b8d9;border-radius:0 6px 6px 0;margin:16px 0}
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.bio-status.off-label{background:#f4effa;border-color:#ded0ef;color:#66527e}
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@media(prefers-reduced-motion:reduce){.bio-sleep .bio-workspace{animation:none}}

.bio-sleep .bio-difficulty-control{margin:0 0 22px}.bio-sleep .bio-difficulty-control .bio-filters button{padding:8px 14px;min-height:42px}
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.bio-sleep .bio-empty-selection h2{font-size:1.2rem;line-height:1.4;margin:0 0 9px}.bio-sleep .bio-empty-selection p{color:#5d6f88;font-size:.9375rem;margin:0 0 20px;max-width:750px}
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.bio-sleep .bio-empty-actions button:focus-visible{outline:2px solid var(--bio-blue);outline-offset:3px}
.bio-sleep .bio-sleep-coverage{margin:16px 0;border-top:1px solid #e1e7f1;padding-top:13px}.bio-sleep .bio-sleep-coverage>strong{font-size:.875rem;color:#435e87}.bio-sleep .bio-sleep-coverage p{font-size:.875rem;line-height:1.6;margin:5px 0 6px;color:#526680}.bio-sleep .bio-sleep-coverage a{font-size:.8125rem;color:var(--bio-blue);text-decoration:underline;text-underline-offset:3px}
.bio-sleep .bio-outcome-context{margin:18px 0 12px;padding-left:12px;border-left:2px solid #8ca7d3}.bio-sleep .bio-outcome-context strong{font-size:.875rem;color:#435e87}.bio-sleep .bio-outcome-context p{font-size:.875rem;line-height:1.6;color:#5c6f88;margin:5px 0 0}
@media(max-width:650px){.bio-sleep .bio-difficulty-control .bio-filters{gap:6px}.bio-sleep .bio-difficulty-control .bio-filters button{padding:8px 11px}.bio-sleep .bio-empty-selection{padding:23px 18px}}
@media(prefers-reduced-motion:reduce){.bio-sleep .bio-empty-selection{animation:none}}

.bio-sleep .bio-coverage-compact{margin:13px 0 16px;padding-top:12px}.bio-sleep .bio-coverage-chips{display:flex;flex-wrap:wrap;gap:6px;margin-top:8px}
.bio-sleep .bio-coverage-chips>span{display:inline-block;font-size:.75rem;line-height:1.4;padding:4px 8px;border:1px solid #d4dfee;border-radius:5px;background:#f6f8fc;color:#526a8e}
.bio-sleep .bio-coverage-context{margin:5px 0 0}.bio-sleep .bio-coverage-context>summary{font-size:.8125rem;font-weight:500;color:var(--bio-blue);padding:6px 0;line-height:1.5;gap:12px}.bio-sleep .bio-coverage-context>summary:after{font-size:1rem}
.bio-sleep .bio-coverage-context[open]>summary{margin-bottom:5px}.bio-sleep .bio-coverage-context .bio-guideline-context{margin:12px 0 0}.bio-sleep .bio-coverage-compact>.bio-coverage-note{font-size:.8125rem;margin-top:8px;color:#67788f}