# Research and maintenance log

- [2026-10-03 Sleep category organization](2026-10-03_sleep_category_organization.md): five condition topics, preserved history hub and inherited evidence; research dates unchanged.

[Home](../README.md) · [Latest highlights](../LATEST.md) · [Initial snapshot](../INITIAL_BRIEF_2026-09-12.md)

Dated records distinguish research checks, scope additions, policy changes and maintenance. Routine unchanged checks stay here without a notification.

- [2026-10-16 scheduled focused research update](2026-10-16_scheduled_research_update.md): 32 active topics, source-dated regulatory and trial updates, one unconfirmed participant signal, and explicit gaps.

- [2026-10-13 scheduled focused research update](2026-10-13_scheduled_research_update.md): all 32 active condition topics, exact source dates, trial/safety updates and explicit gaps.

- [2026-10-09 scheduled focused research update](2026-10-09_scheduled_research_update.md): all 32 active topics, source-dated results, development milestones and explicit unresolved coverage.

- [2026-10-06 scheduled research update](2026-10-06_scheduled_research_update.md): 32-topic focused coverage, conference follow-up, positive/null findings, new trials, timing revisions and source-chain corrections.

- [2026-10-03 sleep–wake reference expansion](2026-10-03_sleep_explorer_expansion.md): ten established/off-label insomnia medicines, mechanism filters and two selected baseline study plots; full watch-run dates unchanged.
- [2026-10-03 focused Medical frontier hair status check](2026-10-03_frontier_hair_status_check.md): PP405 recruiting update, partial rumor corroboration and ABS-201 phase metadata clarification; full watch-run dates unchanged.
- [2026-10-02 scheduled research update](2026-10-02_scheduled_research_update.md): conference results and safety, regulatory steps, new trial registrations, revised forecasts and 28-topic coverage gaps.
- [2026-09-29 scheduled research retry](2026-09-29_scheduled_research_update.md): new programs, preliminary results, trial timing, one informal claim and 28-topic coverage gaps.
- [2026-09-27 scheduled research update](2026-09-27_scheduled_research_update.md): advisory votes, approvals, positive and negative trials, safety, new human programs and 28-topic coverage gaps.
- [2026-09-22 scheduled research retry](2026-09-22_scheduled_research_update.md): new results, regulatory milestones, negative findings, safety detail, recovered baselines and 28-topic coverage gaps.
- [2026-09-19 sleep and hair visualizations](2026-09-19_sleep_hair_visualizations.md): selected mechanisms, trial evidence and source/status clarification; full-topic check dates preserved.
- [2026-09-19 Aesthetics & Dental category merge](2026-09-19_aesthetics_dental_category.md): eight topics under one category; clinical content and research dates preserved.
- [2026-09-18 scheduled research update](2026-09-18_scheduled_research_update.md): new indications, negative and early trial results, safety correction, registrations, attributed informal leads and all-topic coverage gaps.
- [2026-09-14 ad-hoc research update](2026-09-14_ad_hoc_research_update.md): selected new results, regulatory developments, safety corrections and explicit 28-topic coverage gaps.
- [2026-09-13 lipid therapy visualizations](2026-09-13_lipid_visualizations.md)
- [2026-09-13 development-history coverage correction](2026-09-13_development_history_correction.md)
- [2026-09-12 sleep therapies expansion](2026-09-12_sleep_therapies_expansion.md)
- [2026-09-12 reorganization](2026-09-12_reorganization.md)
- [2026-09-12 ssri category](2026-09-12_ssri_category.md)
- [2026-09-12 setup](2026-09-12_setup.md)
- [2026-09-12 rumor policy](2026-09-12_rumor_policy.md)
- [2026-09-12 localized fat expansion](2026-09-12_localized_fat_expansion.md)
- [2026-09-12 category expansion](2026-09-12_category_expansion.md)
- [2026-09-12 baseline](2026-09-12_baseline.md)
- [2026-09-12 aesthetic dental expansion](2026-09-12_aesthetic_dental_expansion.md)

- [September 13, 2026 — expanded medical coverage and genetic screening](2026-09-13_medical_scope_expansion.md): selective baselines for three new and three expanded topics; 28 active topics, preserved research dates and recurring scope.