All therapiesEvidence snapshot 2026-09-13
Weight & glucose

Efsubaglutide alfa

A long-acting protein medicine that activates GLP-1 receptors.

At a glance

Selected evidence in this atlas
Studied use & population

Chinese adults with overweight or obesity without diabetes

Study context
Approval & development

Approved for T2D in China; phase 2b/3 obesity program ongoing.

Status sourceStatus & indications
Selected efficacy evidence

10.58% reported weight loss · 3.61% loss with placebo · 18 weeks

ENLIGHT phase 2b · Phase 2b · sponsor · 20 mg once weekly · Other / incompletely specified

Evidence & limitations
Important safety context

Mostly mild/moderate GI events; no premature AE discontinuations or drug-related serious events.

Safety context
Next milestone

A next milestone is not summarized for this therapy.

Milestone details

Study results apply to their own population, dose and analysis. They do not establish a ranking between therapies.

Evidence in the atlas

1 result

Each result belongs to its own study population, dose and analysis. Open a result for its chart, comparator, safety findings and limitations.

Weight loss

ENLIGHT phase 2b

10.58% reported weight loss · 3.61% loss with placebo · 18 weeks

20 mg once weekly

Chinese adults with overweight or obesity without diabetes

Not specified in public report Approved for T2D in China; phase 2b/3 obesity program ongoing.

Safety context

Mostly mild/moderate GI events; no premature AE discontinuations or drug-related serious events.

Limitations: Conference abstract; exact estimand not reported; distinct molecule from efpeglenatide.

Biology & identity

Status in this atlas: Approved for T2D in China; phase 2b/3 obesity program ongoing. Status source

Hormone activity

A long-acting protein medicine that activates GLP-1 receptors.

Diabegone (怡诺轻)
Commercial diabetes brand in Mainland China and Macau; the higher-dose obesity regimen is investigational. · injection

Guangzhou Innogen Pharmaceutical Group · Originator, developer and commercial supplier; also developing obesity and MASH indications.

Uses, doses and availability depend on the formulation, indication and country. Study doses below describe research; they are not prescribing instructions.

The molecule

A long-acting protein medicine that activates GLP-1 receptors.
Structure not yet verified

Structure not verified

A long-acting protein medicine that activates GLP-1 receptors.

Shown: Protein drug / fusion construct

An exact-drug structure was not verified in this review. The named PubChem lookup did not return a compound record; no related hormone or analogue is substituted.

Efsubaglutide alfa

Development timeline

Next milestone

A next milestone is not summarized for this therapy. This does not mean development has ended.

Development history3 selected milestones

Efsubaglutide alfa · compound history across indications

Selected milestones only. Earlier studies may be missing; the first listed date should not be interpreted as the start of development.

  1. Mainland-China diabetes approval

    NMPA approved efsubaglutide alfa injection for adults with type 2 diabetes.

    Source
  2. Macau diabetes approval

    Innogen's company history records approval in Macau for adult type 2 diabetes.

    Source
  3. ENLIGHT obesity results reported

    The phase 2b conference abstract reported results in adults with overweight or obesity; obesity remains distinct from the approved diabetes indication.

    Source

Selected sources checked Sep 13, 2026. This is not an exhaustive history.